Article
Oral administration of live virus protects susceptible mice from developing Theiler's virus-induced demyelinating disease.
Virology - 15 Sept 2007
Kang Bong-Su, Yahikozawa Hiroyuki, Koh Chang-Sung, Kim Byung S
Abstract excerpt
Intracerebral infection of susceptible mouse strains with Theiler's murine encephalomyelitis virus (TMEV) results in an immune-mediated demyelinating disease similar to human multiple sclerosis. TMEV infection is widely spread via fecal-oral routes among wild mouse populations, yet these infected mice rarely develop clinical disease. Oral vaccination has often been used to protect the host against many different...
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