Article
Failure to replicate effect of Kibra on human memory in two large cohorts of European origin.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2008
Need Anna C, Attix Deborah K, McEvoy Jill M, Cirulli Elizabeth T, Linney Kristen N, Wagoner Ana Patricia, Gumbs Curtis E, Giegling Ina, Möller Hans-Jürgen, Francks Clyde, Muglia Pierandrea, Roses Allen, Gibson Greg, Weale Mike E, Rujescu Dan, Goldstein David B
Abstract excerpt
It was recently suggested that the Kibra polymorphism rs17070145 has a strong effect on multiple episodic memory tasks in humans. We attempted to replicate this using two cohorts of European genetic origin (n = 319 and n = 365). We found no association with either the original SNP or a set of tagging SNPs in the Kibra gene with multiple verbal memory tasks, including one that was an exact replication (Auditory...
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