KIBRA single nucleotide polymorphism is associated with hippocampal subfield volumes and cognition across development.

doi:10.1007/s00429-023-02716-w

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Article

KIBRA single nucleotide polymorphism is associated with hippocampal subfield volumes and cognition across development.

Brain structure & function - 1 Jan 2024

Homayouni Roya, Daugherty Ana M, Yu Qijing, Raz Naftali, Ofen Noa

Abstract excerpt

The hippocampus (Hc) consists of cytoarchitectonically and functionally distinct subfields: dentate gyrus (DG), cornu ammonis (CA1-3), and subiculum. In adults, a single nucleotide polymorphism (rs17070145, C→ T) in KIBRA, a gene encoding the eponymous (KIdney-BRAin) protein, is associated with variability in Hc subfield volumes and episodic memory. T-allele carriers have larger DG and CA volumes and better...

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PMID: 37853296
DOI: 10.1007/s00429-023-02716-w

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