Article
IL-10 overexpression decreases inflammatory mediators and promotes regenerative healing in an adult model of scar formation.
The Journal of investigative dermatology - 1 Jul 2008
Peranteau William H, Zhang Liping, Muvarak Nidal, Badillo Andrea T, Radu Antoneta, Zoltick Philip W, Liechty Kenneth W
Abstract excerpt
Adult wound healing is characterized by an exuberant inflammatory response and scar formation. In contrast, scarless fetal wound healing has diminished inflammation, a lack of fibroplasia, and restoration of normal architecture. We have previously shown that fetal wounds produce less inflammatory...
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