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Article

Epidermal growth factor receptor (EGFR) biology and human oral cancer.

1 Apr 1999

Abstract excerpt

Dysregulation of the epidermal growth factor receptor (EGFR) is one of the most frequently studied molecular events leading to oral carcinogenesis. Overexpression of EGFR is a common event in many human solid tumors. Elevated levels of EGFR mRNA in human cancer occur with and without gene rearrangement. Structural alterations in the receptor can also result in the dysregulation of the EGFR pathway. EGFR...

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Identifiers

PMID: 10212811
DOI: 10.14670/hh-14.491

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