Article
Design and validation of methods searching for risk factors in genotype case-control studies.
Journal of computational biology : a journal of computational molecular cell biology - 1 Jan 2000
Brinza Dumitru, Zelikovsky Alexander
Abstract excerpt
Accessibility of high-throughput genotyping technology allows genome-wide association studies for common complex diseases. This paper addresses two challenges commonly facing such studies: (i) searching an enormous amount of possible gene interactions and (ii) finding reproducible associations. T...
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