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Article

Flurazepam inhibits the P-glycoprotein transport function: an insight to revert multidrug-resistance phenotype.

European journal of pharmacology - 26 Feb 2008

Lima Sofia A C, Tavares Joana, Gameiro Paula, de Castro Baltazar, Cordeiro-da-Silva Anabela

Abstract excerpt

P-glycoprotein mediated drug transport may lead to a multidrug resistance phenotype often associated with a poor response to the successful treatment of a variety of human disorders. Several agents have been found to modulate P-glycoprotein drug resistance, most probably by blocking its transport function. The aim of this study was to examine the effects of some benzodiazepines (bromazepam, chlordiazepoxide,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18190907
DOI: 10.1016/j.ejphar.2007.11.045

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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