Article
Looking for polycystic ovary syndrome genes: rational and best strategy.
Seminars in reproductive medicine - 1 Jan 2008
Goodarzi Mark O
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a common, complex genetic disorder. Its inherited basis was established by studies demonstrating an increased prevalence of PCOS and hyperandrogenemia, insulin resistance, and disordered insulin secretion in relatives of women with PCOS. To date, efforts in elucidating the genetic basis of PCOS have focused on candidate genes chosen from logical pathways, such as steroid...
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