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Article

Genetic determinants of polycystic ovary syndrome: progress and future directions.

Fertility and sterility - 1 Jul 2016

Jones Michelle R, Goodarzi Mark O

Abstract excerpt

The field of the genetics of polycystic ovary syndrome (PCOS) has relatively recently moved into the era of genome-wide association studies. This has led to the discovery of 16 robust loci for PCOS. Some loci contain genes with clear roles in reproductive (LHCGR, FSHR, and FSHB) and metabolic (INSR and HMGA2) dysfunction in the syndrome. The next challenge facing the field is the identification of causal variants...

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Source

Identifiers

PMID: 27179787
DOI: 10.1016/j.fertnstert.2016.04.040

Genes

FSHB
FSHR
HMGA2
INSR
LHCGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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