Article
c-Jun supports ribosomal RNA processing and nucleolar localization of RNA helicase DDX21.
The Journal of biological chemistry - 14 Mar 2008
Holmström Tim H, Mialon Antoine, Kallio Marko, Nymalm Yvonne, Mannermaa Leni, Holm Tina, Johansson Henrik, Black Elizabeth, Gillespie David, Salminen Tiina A, Langel Ulo, Valdez Benigno C, Westermarck Jukka
Abstract excerpt
The molecular mechanisms by which the AP-1 transcription factor c-Jun exerts its biological functions are not clearly understood. In addition to its well established role in transcriptional regulation of gene expression, several reports have suggested that c-Jun may also regulate cell behavior by non-transcriptional mechanisms. Here, we report that small interfering RNA-mediated depletion of c-Jun from mammalian...
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