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Article

Apoptic renal carcinoma cells are better inducers of cross-presenting activity than their primary necrotic counterpart.

International journal of immunopathology and pharmacology - 1 Jan 2000

D' Hooghe E, Buttiglieri S, Bisignano G, Brusa D, Camussi G, Matera L

Abstract excerpt

Vaccination with tumor-loaded dendritic cells (DC) is a promising treatment strategy for patients with renal cell carcinoma (RCC). Cells undergoing cell death proved useful as a source of tumor antigen for DC loading. Both apoptotic and necrotic tumor cells have been shown to efficiently load RCC-tumor antigens on DC. However, no direct comparison of these two kinds of death has been attempted in the same RCC. We...

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Share to Antigen-Presenting Cells
Share to Antigens, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Renal Cell

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Source

Identifiers

PMID: 18179743
DOI: 10.1177/039463200702000406

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