Article
Recent approaches to the prioritization of candidate disease genes.
Wiley interdisciplinary reviews. Systems biology and medicine - 1 Jan 2000
Doncheva Nadezhda T, Kacprowski Tim, Albrecht Mario
Abstract excerpt
Many efforts are still devoted to the discovery of genes involved with specific phenotypes, in particular, diseases. High-throughput techniques are thus applied frequently to detect dozens or even hundreds of candidate genes. However, the experimental validation of many candidates is often an expensive and time-consuming task. Therefore, a great variety of computational approaches has been developed to support...
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