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Article

Environmental epigenomics and disease susceptibility.

Nature reviews. Genetics - 1 Apr 2007

Jirtle Randy L, Skinner Michael K

Abstract excerpt

Epidemiological evidence increasingly suggests that environmental exposures early in development have a role in susceptibility to disease in later life. In addition, some of these environmental effects seem to be passed on through subsequent generations. Epigenetic modifications provide a plausible link between the environment and alterations in gene expression that might lead to disease phenotypes. An increasing...

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Identifiers

PMID: 17363974
DOI: 10.1038/nrg2045
PMCID: PMC5940010

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Source receipt: pubmed, retrieved 7 Sept 2026.

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