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Article

Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis.

Human genetics - 1 Feb 2008

Masson Emmanuelle, Chen Jian-Min, Scotet Virginie, Le Maréchal Cédric, Férec Claude

Abstract excerpt

Extensive genetic studies of chronic pancreatitis over the past decade have highlighted the importance of a tightly regulated balance between activation and inactivation of trypsin within the pancreas to disease susceptibility and resistance. The recent identification of chymotrypsin C (CTRC) as...

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Source

Identifiers

PMID: 18172691
DOI: 10.1007/s00439-007-0459-3

Genes

CTRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18172691-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis.PMID 18172691Read ↗

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A conservative assessment of the major genetic causes of idiopathic chronic pancreatitis: data from a comprehensive analysis of PRSS1, SPINK1, CTRC and CFTR genes in 253 young French patients.Semantic proximity Read ↗

Genetic and functional analysis of chymotrypsin-like protease (CTRL) in chronic pancreatitis.Semantic proximity Read ↗

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