Article
Neuropsychiatric symptoms of fragile X syndrome: pathophysiology and pharmacotherapy.
CNS drugs - 1 Jan 2004
Tsiouris John A, Brown W Ted
Abstract excerpt
Fragile X syndrome is the leading inherited form of mental retardation, and second only to Down's syndrome as a cause of mental retardation attributable to an identifiable genetic abnormality. Fragile X syndrome is caused by a defect in the fragile X mental retardation 1 gene (FMR1), located near the end of the long arm of the X chromosome. FMR1 normally synthesises the fragile X protein (FMRP), but mutations in...
Topics
- Animals
- Behavioral Symptoms
- Family Health
- Fragile X Mental Retardation Protein
- Fragile X Syndrome
- Humans
- Mental Disorders
- Mutation
- Nerve Tissue Proteins
- Psychotropic Drugs
- RNA-Binding Proteins