Article
Association of CAPN10 gene with insulin sensitivity, glucose tolerance and renal function in essential hypertensive patients.
Clinica chimica acta; international journal of clinical chemistry - 5 Aug 2010
Zhou Xiaoou, Wang Yan, Zhang Yi, Gao Pingjin, Zhu Dingliang
Abstract excerpt
BACKGROUND: Essential hypertension (EH) is a common disorder, which can increase the risk for type 2 diabetes (T2D). Calpain-10 (CAPN10) gene was the first candidate gene of T2D identified through genome-wide linkage and positional cloning, but few works have focused on the relationship of CAPN10 with impaired fasting glucose (IFG) or impaired glucose tolerance (IGT) in EH patients. METHODS: To identify the...
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