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Article

Dynamic behavior of hepatitis C virus quasispecies in a long-term culture of the three-dimensional radial-flow bioreactor system.

Journal of virological methods - 1 Mar 2008

Murakami Kyoko, Inoue Yasushi, Hmwe Su-Su, Omata Kazuhiko, Hongo Tomokatsu, Ishii Koji, Yoshizaki Sayaka, Aizaki Hideki, Matsuura Tomokazu, Shoji Ikuo, Miyamura Tatsuo, Suzuki Tetsuro

Abstract excerpt

Hepatitis C virus (HCV) exists in infected individuals as quasispecies, usually consisting of a dominant viral isolate and a variable mixture of related, yet genetically distinct, variants. A prior HCV infection system was developed using human hepatocellular carcinoma cells cultured in the three-dimensional radial-flow bioreactor (RFB), in which the cells retain morphological appearance and their differentiated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18164425
DOI: 10.1016/j.jviromet.2007.11.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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