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Article

ATP binding by monarch-1/NLRP12 is critical for its inhibitory function.

Molecular and cellular biology - 1 Mar 2008

Ye Zhengmao, Lich John D, Moore Chris B, Duncan Joseph A, Williams Kristi L, Ting Jenny P-Y

Abstract excerpt

The recently discovered nucleotide binding domain-leucine rich repeat (NLR) gene family is conserved from plants to mammals, and several members are associated with human autoinflammatory or immunodeficiency disorders. This family is defined by a central nucleotide binding domain that contains the highly conserved Walker A and Walker B motifs. Although the nucleotide binding domain is a defining feature of this...

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Identifiers

PMID: 18160710
DOI: 10.1128/MCB.01468-07
PMCID: PMC2258772

Genes

NLRP12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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