Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ATP-dependent effector-like functions of RIG-I-like receptors.

Molecular cell - 7 May 2015

Yao Hui, Dittmann Meike, Peisley Alys, Hoffmann Hans-Heinrich, Gilmore Rachel H, Schmidt Tobias, Schmidt-Burgk Jonathan, Hornung Veit, Rice Charles M, Hur Sun

Abstract excerpt

The vertebrate antiviral innate immune system is often considered to consist of two distinct groups of proteins: pattern recognition receptors (PRRs) that detect viral infection and induce the interferon (IFN) signaling, and effectors that directly act against viral replication. Accordingly, previous studies on PRRs, such as RIG-I and MDA5, have primarily focused on their functions in viral double-stranded RNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DEAD Box Protein 58
Share to DEAD-box RNA Helicases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to eIF-2 Kinase

Share to Interferon-beta

Share to Interferon-Induced Helicase, IFIH1

Share to Receptors, Pattern Recognition

Share to RNA, Double-Stranded

Share to Virus Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 25891073
DOI: 10.1016/j.molcel.2015.03.014
PMCID: PMC4427555

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ATP-dependent effector-like functions of RIG-I-like receptors.PMID 25891073Read ↗

Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptorsSemantic proximity Read ↗

PKR Transduces MDA5-Dependent Signals for Type I IFN Induction.Semantic proximity Read ↗

Discrimination of cytosolic self and non-self RNA by RIG-I-like receptorsSemantic proximity Read ↗

Cytoplasmic RNA sensors and their interplay with RNA-binding partners in innate antiviral response: theme and variationsSemantic proximity Read ↗

In Vivo Ligands of MDA5 and RIG-I in Measles Virus-Infected CellsSemantic proximity Read ↗

RIG-I and dsRNA-Induced IFNβ ActivationSemantic proximity Read ↗

Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling.Semantic proximity Read ↗

Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants.Semantic proximity Read ↗

Analysis of Porcine RIG-I Like Receptors Revealed the Positive Regulation of RIG-I and MDA5 by LGP2.Semantic proximity Read ↗

A central role for RNA in the induction and biological activities of type 1 interferonsSemantic proximity Read ↗

Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate ImmunitySemantic proximity Read ↗

Dengue virus replicative-form dsRNA is recognized by RIG-I and MDA5 cooperatively to activate innate immunitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.