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Article

Sporadic inclusion body myositis: a continuing puzzle.

Neuromuscular disorders : NMD - 1 Jan 2008

Needham M, Mastaglia F L

Abstract excerpt

There is now compelling evidence that sporadic inclusion body myositis (sIBM) is a muscle-specific autoimmune disease in which both T and B-cells play a part and in which both cytotoxic muscle fibre necrosis and degeneration occur. However the factors responsible for breakdown of immune tolerance and the nature of the target antigens expressed by muscle fibres remain unknown. Genetic factors are known to...

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PMID: 18160291
DOI: 10.1016/j.nmd.2007.11.001

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UBB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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