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Article

In vitro evaluation of photosensitivity risk related to genetic polymorphisms of human ABC transporter ABCG2 and inhibition by drugs.

Drug metabolism and pharmacokinetics - 1 Dec 2007

Tamura Ai, Onishi Yuko, An Ran, Koshiba Shoko, Wakabayashi Kanako, Hoshijima Kazuyuki, Priebe Waldemar, Yoshida Takashi, Kometani Satoshi, Matsubara Takayoshi, Mikuriya Kenta, Ishikawa Toshihisa

Abstract excerpt

Since porphyrins are regarded as endogenous substrates for the ATP-binding cassette (ABC) transporter ABCG2, it is hypothesized that functional impairment owing to genetic polymorphisms or inhibition of ABCG2 by drugs may result in a disruption of cellular porphyrin homeostasis. In the present st...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18159130
DOI: 10.2133/dmpk.22.428

Genes

ABCG2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18159130-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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In vitro evaluation of photosensitivity risk related to genetic polymorphisms of human ABC transporter ABCG2 and inhibition by drugs.PMID 18159130Read ↗

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