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Article

Role of the specifically targeted lysine residues in the glycation dependent loss of chaperone activity of alpha A- and alpha B-crystallins.

Molecular and cellular biochemistry - 1 Mar 2008

Abraham Edathara C, Huaqian Jin, Aziz Atya, Kumarasamy Anbarasu, Datta Poppy

Abstract excerpt

Earlier studies have shown significant loss of chaperone activity in alpha-crystallin from diabetic lenses. In vitro glycation studies have suggested that glycation of alpha-crystallin could be the major cause of chaperone activity loss. The following lysine (K) residues in alpha-crystallin have...

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Identifiers

PMID: 18158587
DOI: 10.1007/s11010-007-9685-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18158587-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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