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Article

OGG1 expression and OGG1 Ser326Cys polymorphism and risk of lung cancer in a prospective study.

Mutation research - 1 Mar 2008

Hatt Lotte, Loft Steffen, Risom Lotte, Møller Peter, Sørensen Mette, Raaschou-Nielsen Ole, Overvad Kim, Tjønneland Anne, Vogel Ulla

Abstract excerpt

Oxidative DNA damage is believed to be implicated in lung carcinogenesis. 8-OxodG is a mutagenic and abundant oxidative modification induced in DNA. OGG1, NEIL1 and MUTYH are all involved in the repair and prevention of 8-oxodG-derived mutations and may be up-regulated by oxidative stress. The polymorphism OGG1 Ser326Cys has in some studies been associated with risk of lung cancer. In a population-based cohort of...

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Source

Identifiers

PMID: 18155253
DOI: 10.1016/j.mrfmmm.2007.11.002

Genes

OGG1
MUTYH
NEIL1
NUDT1

Provenance

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OGG1 expression and OGG1 Ser326Cys polymorphism and risk of lung cancer in a prospective study.PMID 18155253Read ↗

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hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

The association between OGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis of 27 studies.Semantic proximity Read ↗

The hOGG1 Ser326Cys polymorphism and lung cancer risk: a meta-analysis.Semantic proximity Read ↗

Association between the hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis based on 22,475 subjects.Semantic proximity Read ↗

Interactions between the OGG1 Ser326Cys polymorphism and intake of fruit and vegetables in relation to lung cancer.Semantic proximity Read ↗

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DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326.Semantic proximity Read ↗

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