Article
Validation of biomarkers associated with 5-fluorouracil and thymidylate synthase in colorectal cancer
1 Jan 2008
Abstract excerpt
Previous studies from our laboratory have identified a number of genes associated with chemosensitivity to 5-fluorouracil (5-FU) using an in vitro colon cancer cell line model. In this study, the in vivo significance of several marker genes in terms of prognostic potential was evaluated using colorectal cancer patient samples. Eight marker genes were selected based on their functional roles and significant fold...
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