Article
Gene expression and promoter polymorphisms of DNA methyltransferase 3B in nasopharyngeal carcinomas in Taiwanese people: a case-control study.
Oncology reports - 1 Jan 2008
Chang Kai-Ping, Hao Sheng-Po, Tsang Ngan-Ming, Chang Yu-Liang, Cheng Ming-Huei, Liu Chun-Ting, Lee Yun-Shien, Tsai Chia-Lung, Lee Ta-Jen, Wang Tzu-Hao, Tsai Chi-Neu
Abstract excerpt
Overexpression of the DNA methyltransferase 3B (DNMT3B) gene and its effect on carcinogenesis has been demonstrated for various types of cancer. Recently, three single nucleotide polymorphisms (SNPs) of the DNMT3B promoter region, C46359T (-149C>T), -283T>C, and -579G>T have also been reported to...
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