Article
Expression of the transcription factor Zfp191 during embryonic development in the mouse.
Gene expression patterns : GEP - 1 Feb 2008
Khalfallah Olfa, Faucon-Biguet Nicole, Nardelli Jeannette, Meloni Rolando, Mallet Jacques
Abstract excerpt
The human zinc finger protein 191 (ZNF191) is a Krüppel-like protein and can specifically interact with the widespread TCAT motif which constitutes the HUMTH01 microsatellite in the tyrosine hydroxylase (TH) gene (encoding the rate-limiting enzyme in the synthesis of catecholamines). Allelic variations of HUMTH01 are known to have a quantitative silencing effect on TH gene expression and to correlate with...
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