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Article

Evidence of a genetic contribution to lung function decline in asthma.

The Journal of allergy and clinical immunology - 1 Sept 2011

Koppelman Gerard H, Sayers Ian

Abstract excerpt

There has been great progress in identifying new asthma susceptibility genes. In asthmatic subjects there is variable airway remodeling that includes features such as smooth muscle hypertrophy/hyperplasia, basement membrane thickening, and increased extracellular matrix deposition. Does airway remodeling have a genetic contribution in asthma? Data from different murine strains suggest there is a genetic...

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Source

Identifiers

PMID: 21752436
DOI: 10.1016/j.jaci.2011.05.036

Genes

FEV
ADAM33
ESR1
PLAUR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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