Simultaneous detection of multiple single-base alleles at a polymorphic site.

Article

Simultaneous detection of multiple single-base alleles at a polymorphic site.

BioTechniques - 1 Dec 1991

Dutton C, Sommer S S

Abstract excerpt

PCR amplification of multiple specific alleles (PAMSA) is a rapid method of detecting single-base polymorphisms. We demonstrate its utility by detecting a polymorphism in an Alu sequence in the factor IX gene.

Topics

Alleles
Base Sequence
DNA
Factor IX
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic
Repetitive Sequences, Nucleic Acid

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