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Article

Characterization of the patterns of polymorphism in a "cryptic repeat" reveals a novel type of hypervariable sequence.

American journal of human genetics - 1 Aug 1993

Jacobson D P, Schmeling P, Sommer S S

Abstract excerpt

Alternating purine and pyrimidine repeats (RY(i)) are an abundant source of polymorphism. The subset with long tandem repeats of GT or AC (GT(i)) have been studied extensively, but cryptic RY(i) (i.e., no single tandem repeat predominates) have received little attention. The factor IX gene has a polymorphic cryptic RY(i) of 142-216 bp. Previously, there were four known polymorphic alleles, of the form AB, A2B,...

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Source

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Identifiers

PMID: 8328460
PMCID: PMC1682338

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