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Article

Exploratory analysis of Fas gene polymorphisms in pediatric osteosarcoma patients.

Journal of pediatric hematology/oncology - 1 Dec 2007

Koshkina Nadezhda V, Kleinerman Eugenie S, Li Guojun, Zhao Chong C, Wei Qingyi, Sturgis Erich M

Abstract excerpt

Defective apoptosis signaling by the Fas pathway has carcinogenic implications. We analyzed 123 pediatric patients with osteosarcoma for Fas single nucleotide polymorphisms: 2 of the promoter region (-1377 G>A and -670 A>G) and 2 of the coding region (exon 3 18272 A>G and exon 7 22628 C>T). As a...

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Source

Identifiers

PMID: 18090928
DOI: 10.1097/MPH.0b013e3181581506

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18090928-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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