Article
Genetic variation at chromosome 8q24 in osteosarcoma cases and controls.
Carcinogenesis - 1 Aug 2010
Mirabello Lisa, Berndt Sonja I, Seratti Guillermo F, Burdett Laurie, Yeager Meredith, Chowdhury Salma, Teshome Kedest, Uzoka Arinze, Douglass Chester, Hayes Richard B, Hoover Robert N, Savage Sharon A
Abstract excerpt
Osteosarcoma is a primary bone malignancy that typically occurs during the pubertal growth spurt. Only a few small association studies have evaluated common germ line variation in individuals with osteosarcoma. The 8q24 chromosomal region contains several loci that are associated with risk of many different cancers. We conducted an association study of common single-nucleotide polymorphisms (SNPs) across 8q24 to...
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