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Article

Dopamine gene predicts the brain's response to dopaminergic drug.

The European journal of neuroscience - 1 Dec 2007

Cohen Michael X, Krohn-Grimberghe Artus, Elger Christian E, Weber Bernd

Abstract excerpt

Dopamine is critical for reward-based decision making, yet dopaminergic drugs can have opposite effects in different individuals. This apparent discrepancy can be accounted for by hypothesizing an 'inverted-U' relationship, whereby the effect of dopamine agents depends on baseline dopamine system functioning. Here, we used functional MRI to test the hypothesis that genetic variation in the expression of dopamine...

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Source

Identifiers

PMID: 18088284
DOI: 10.1111/j.1460-9568.2007.05947.x

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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