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Article

Association between promoter and coding region mutations of UDP-glucuronosyltransferase 1A1 and beta-thalassemia/Hb E with cholelithiasis.

European journal of haematology - 1 Apr 2008

Tankanitlert Jeeranut, Morales Noppawan P, Fucharoen Pranee, Fucharoen Suthat, Chantharaksri Udom

Abstract excerpt

BACKGROUND AND OBJECTIVES: Cholelithiasis has been observed with high incidence in beta-thalassemia/hemoglobin E (beta-thal/Hb E). Recent studies have shown that a variant TATA-box in the promoter region of the UDP-glucuronosyltransferase 1A1 (UGT1A1) gene is associated with the development of cholelithiasis. The coding region mutation (G71R) of the UGT1A1 gene was higher in Asians than those in Caucasians. The...

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PMID: 18081723
DOI: 10.1111/j.1600-0609.2007.01010.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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