Article
Effect of bilirubin UDP glucuronosyltransferase 1 gene TATA box genotypes on serum bilirubin concentrations in chronic liver injuries.
Hepatology (Baltimore, Md.) - 1 Sept 2000
Doyama H, Okada T, Kobayashi T, Suzuki A, Takeda Y, Mabuchi H
Abstract excerpt
TATA box abnormality in the promoter region of the bilirubin UDP glucuronosyltransferase 1 gene has been reported to cause Gilbert's syndrome in white subjects. It has also been reported that the majority of Japanese patients with Gilbert's syndrome are heterozygous for Gly71Arg in the coding region of this gene. On the other hand, some patients with chronic hepatitis often show signs of unexpected...
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