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Article

FK506 protects neurons following peripheral nerve injury via immunosuppression.

Cellular and molecular neurobiology - 1 Dec 2007

Saxena Kapil, Patro Nisha, Patro Ishan

Abstract excerpt

In this study, we have evaluated neuroprotective effect of an immunosuppressant immunophilin ligand, FK506, in the sciatic nerve injury model in rats. FK506 was injected to the sciatic nerve transected 3-month-old female Wistar rats (2 mg/kg/day starting 1 day prior to sciatic nerve injury up to 7 day post operation). Equal number of sciatic nerve transected animals served as injured untreated controls. The...

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Source

Identifiers

PMID: 18080746
DOI: 10.1007/s10571-007-9221-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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