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Article

Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation.

The Journal of investigative dermatology - 1 Jun 2008

Sklyarova Tatyana, Bonné Stefan, D'Hooge Petra, Denecker Geertrui, Goossens Steven, De Rycke Riet, Borgonie Gaetan, Bösl Michael, van Roy Frans, van Hengel Jolanda

Abstract excerpt

We generated mice deficient in plakophilin-3 (PKP3), a member of the Armadillo-repeat family and a component of desmosomes and stress granules in epithelial cells. In these mice, several subsets of hair follicles (HFs) had morphological abnormalities, and the majority of awl and auchene hair shaf...

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Source

Identifiers

PMID: 18079750
DOI: 10.1038/sj.jid.5701189

Genes

PKP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18079750-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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