Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Coding region polymorphisms in the CHFR mitotic stress checkpoint gene are associated with colorectal cancer risk.

Cancer letters - 18 Feb 2008

Kang Hio Chung, Kim Il-Jin, Jang Sang-Geun, Hong Seung-Hyun, Hwang Jung-Ah, Shin Hai-Rim, Park Jae-Gahb

Abstract excerpt

CHFR was recently identified as an early mitotic checkpoint that delays transition to metaphase in response to mitotic stress. Although studies have shown that CHFR is relevant to tumorigenesis, no previous report has investigated whether polymorphisms in the CHFR gene are associated with the ris...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle Proteins
Share to Microsatellite Instability
Share to Mitosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Metastasis

Share to Neoplasm Proteins

Share to Neoplasm Staging

Share to Poly-ADP-Ribose Binding Proteins

Share to Ubiquitin-Protein Ligases

Source

Identifiers

PMID: 18079053
DOI: 10.1016/j.canlet.2007.10.036

Genes

CHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18079053-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Coding region polymorphisms in the CHFR mitotic stress checkpoint gene are associated with colorectal cancer risk.PMID 18079053Read ↗

CHFR gene variations: A novel cause for hereditary cancer predisposition?Semantic proximity Read ↗

Association of CHFR Promoter Methylation with Disease Recurrence in Locally Advanced Colon CancerSemantic proximity Read ↗

CHFR gene is neither mutated nor hypermethylated in ovarian cancer.Semantic proximity Read ↗

Altered expression of the early mitotic checkpoint protein, CHFR, in breast cancers: implications for tumor suppression.Semantic proximity Read ↗

The mutational and transcriptional status of RYR in CRC and its indication for prognosis.Semantic proximity Read ↗

Implication of TYMP genetic variation on the prognosis of patients with colorectal cancer who received capecitabine-based adjuvant chemotherapy after surgical resection: a real-world exploratory studySemantic proximity Read ↗

Inactivating mutations targeting the chfr mitotic checkpoint gene in human lung cancer.Semantic proximity Read ↗

Association of HOTAIR rs1899663 G>T Polymorphism with Colorectal Cancer in the Turkish Population: A Case-Control Study.Semantic proximity Read ↗

[The influence of Thymidine Phosphorylase genetic variation on clinical outcomes and safety of colorectal cancer patients received adjuvant chemotherapy after R0 resection].Semantic proximity Read ↗

CHFR hypermethylation, a frequent event in acute myeloid leukemia, is independently associated with an adverse outcome.Semantic proximity Read ↗

CHFR promoter hypermethylation in colon cancer correlates with the microsatellite instability phenotypeSemantic proximity Read ↗

Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.