Article
Lack of association between polymorphisms in p53 gene and spermatogenetic failure in a Chinese population.
Andrologia - 1 Dec 2007
Lu N X, Xia Y K, Gu A H, Liang J, Wang S L, Wang X R
Abstract excerpt
Although various genetic factors have been demonstrated in human male infertility, many genetic causes involving gene variants for the idiopathic male infertility have not yet been elucidated. P53 gene is involved in the meiosis of the male rat and mice, which suggested that p53 plays a critical role in spermatogenesis. To examine whether the codon72 polymorphism and IVS7+72C>T polymorphism of the human p53 gene...
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