Article
Genetic variants of eNOS gene may modify the susceptibility to idiopathic male infertility.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Aug 2013
Ying Hou-Qun, Pu Xiao-Ying, Liu Shuo-Ran, A Zhou-Cun
Abstract excerpt
In testis, eNOS is responsible for synthesis of nitric oxide (NO) which is an essential gas message regulator in spermatogenesis, suggesting that eNOS gene plays a role in normal spermatogenesis and the genetic variants of eNOS gene may be potential genetic risk factors of spermatogenesis impairment. In this study, the polymorphic distributions of three common polymorphism loci including T-786C, 4A4B and G894T in...
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