Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An association study of HFE gene mutation with idiopathic male infertility in the Chinese Han population.

Asian journal of andrology - 1 Jul 2012

Yu Xiao-Ying, Wang Bin-Bin, Xin Zhong-Cheng, Liu Tao, Ma Ke, Jiang Jian, Fang Xiang, Yu Li-Hua, Peng Yi-Feng, Ma Xu

Abstract excerpt

Mutations in the haemochromatosis gene (HFE) influence iron status in the general population of Northern Europe, and excess iron is associated with the impairment of spermatogenesis. The aim of this study is to investigate the association between three mutations (C282Y, H63D and S65C) in the HFE gene with idiopathic male infertility in the Chinese Han population. Two groups of Chinese men were recruited: 444...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthenozoospermia
Share to Azoospermia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Confidence Intervals

Share to Follicle Stimulating Hormone

Share to Hemochromatosis Protein

Share to Luteinizing Hormone

Share to Oligospermia

Share to Testosterone

Source

Open in PubMed Open full text

Identifiers

PMID: 22504868
DOI: 10.1038/aja.2012.1
PMCID: PMC3720068

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An association study of HFE gene mutation with idiopathic male infertility in the Chinese Han population.PMID 22504868Read ↗

Analysis of the hemochromatosis mutations C282Y and H63D in infertile men.Semantic proximity Read ↗

The impact of hemochromatosis mutations and transferrin genotype on gonadotropin serum levels in infertile men.Semantic proximity Read ↗

Hereditary haemochromatosis gene (HFE) H63D mutation shows an association with abnormal sperm motility.Semantic proximity Read ↗

Lack of association between polymorphisms in p53 gene and spermatogenetic failure in a Chinese population.Semantic proximity Read ↗

FSH receptor gene polymorphisms in fertile and infertile Han-Chinese males.Semantic proximity Read ↗

Lack of association between genetic polymorphisms in three folate-related enzyme genes and male infertility in the Chinese population.Semantic proximity Read ↗

[Evaluation of GPx1 Pro198Leu Polymorphism in Idiopathic Male Infertility].Semantic proximity Read ↗

Association of the MTHFR A1298C variant with unexplained severe male infertility.Semantic proximity Read ↗

Relationship between genetic polymorphisms of methylenetetrahydrofolate reductase (C677T, A1298C, and G1793A) as risk factors for idiopathic male infertility.Semantic proximity Read ↗

The SLC19A1 80G>A polymorphism is not associated with male infertility.Semantic proximity Read ↗

Polymorphisms in folate-related enzyme genes in idiopathic infertile Brazilian men.Semantic proximity Read ↗

Association study of human leucocyte antigen-A gene with idiopathic male infertility in Han population of China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.