Article
Genetics of clinical expression in SLE.
Autoimmunity - 1 Dec 2007
Namjou Bahram, Kilpatrick Jeff, Harley John B
Abstract excerpt
Systemic lupus erythematosus (SLE) is the prototype of complex autoimmune diseases and is characterized by extreme breakdown of self-tolerance which results in a wide range of immunologic abnormalities and immune complex formation. Genetic, hormonal and environmental factors are known to contribute to the expression of the disease. SLE is very heterogeneous in clinical manifestations and different autoantibodies...
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