Article
Genetic association analysis of the RTK/ERK pathway with aggressive prostate cancer highlights the potential role of CCND2 in disease progression.
Scientific reports - 3 Jul 2017
Chen Yang, Zhang Qin, Wang Qiuyan, Li Jie, Sipeky Csilla, Xia Jihan, Gao Ping, Hu Yanling, Zhang Haiying, Yang Xiaobo, Chen Haitao, Jiang Yonghua, Yang Yuehong, Yao Ziting, Chen Yinchun, Gao Yong, Tan Aihua, Liao Ming, Schleutker Johanna, Xu Jianfeng, Sun Yinghao, Wei Gong-Hong, Mo Zengnan
Abstract excerpt
The RTK/ERK signaling pathway has been implicated in prostate cancer progression. However, the genetic relevance of this pathway to aggressive prostate cancer at the SNP level remains undefined. Here we performed a SNP and gene-based association analysis of the RTK/ERK pathway with aggressive pro...
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