Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation of Neurogenin 3 is slightly associated with hyperproinsulinaemia and progression toward type 2 diabetes.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Mar 2008

Li J, Bergmann A, Reimann M, Schulze J, Bornstein S R, Schwarz P E H

Abstract excerpt

OBJECTIVE: Transcription factor Neurogenin 3 (NGN3) is considered as a candidate gene for the development of type 2 diabetes. The aim of the current study was to investigate the relevance of NGN3 variants for the clinical spectrum of diabetes development and disease progressions. RESEARCH DESIGN AND METHODS: A total of 552 subjects with increased risk of type 2 diabetes were investigated. They underwent a 75 g...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic Helix-Loop-Helix Transcription Factors
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Germany

Share to Hyperinsulinism

Share to Insulin

Share to Proinsulin

Share to Waist-Hip Ratio

Source

Identifiers

PMID: 18072012
DOI: 10.1055/s-2007-992156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation of Neurogenin 3 is slightly associated with hyperproinsulinaemia and progression toward type 2 diabetes.PMID 18072012Read ↗

NEUROG3 variants and type 2 diabetes in Italians.Semantic proximity Read ↗

Polymorphisms in the neurogenin 3 gene (NEUROG) and their relation to altered insulin secretion and diabetes in the Danish Caucasian population.Semantic proximity Read ↗

Gender and neurogenin3 influence the pathogenesis of ketosis-prone diabetes.Semantic proximity Read ↗

Variants of neurogenin 3 gene are not associated with Type II diabetes in Japanese subjects.Semantic proximity Read ↗

Gli-similar 3 (GLIS3) rs7020763 (C>G) polymorphism in patients with type 2 diabetes mellitus.Semantic proximity Read ↗

GLIS3 rs7020673 and rs10758593 polymorphisms interact in the susceptibility for type 1 diabetes mellitus.Semantic proximity Read ↗

Mutation screening of the neurogenin-3 gene in autosomal dominant diabetes.Semantic proximity Read ↗

Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps.Semantic proximity Read ↗

Interaction of the G protein beta 3 subunit T825 allele and the IRS-1 Arg972 variant in type 2 diabetes.Semantic proximity Read ↗

Mutations in the coding region of the neurogenin 3 gene (NEUROG3) are not a common cause of maturity-onset diabetes of the young in Japanese subjects.Semantic proximity Read ↗

NeuroD/BETA2 gene variability and diabetes: no associations to late-onset type 2 diabetes but an A45 allele may represent a susceptibility marker for type 1 diabetes among Danes. Danish Study Group of Diabetes in Childhood, and the Danish IDDM Epidemiology and Genetics Group.Semantic proximity Read ↗

A polymorphism within the fructosamine-3-kinase gene is associated with HbA1c Levels and the onset of type 2 diabetes mellitus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.