Article
CD72 polymorphism associated with child-onset of idiopathic thrombocytopenic purpura in Chinese patients.
Journal of clinical immunology - 1 May 2008
Xu Jianhui, Lu Shihong, Tao Jie, Zhou Zeping, Chen Zhenping, Huang Ying, Yang Renchi
Abstract excerpt
Idiopathic thrombocytopenic purpura (ITP) is a disease putatively relating to abnormal immune function and auto-antiplatelet immunoglobulin. We examined whether polymorphism of CD72, an inhibitory receptor of B cells, affect the susceptibility to ITP, or associated with the clinical characteristics of ITP. A case-control study was carried out in 206 Chinese ITP patients and 169 healthy controls. The detection of...
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