Article
Resistance to antimicrobial peptides contributes to persistence of Salmonella typhimurium in the C. elegans intestine.
Cellular microbiology - 1 Jun 2008
Alegado Rosanna A, Tan Man-Wah
Abstract excerpt
The human pathogen Salmonella typhimurium can colonize, proliferate and persist in the intestine causing enteritis in mammals and mortality in the nematode Caenorhabditis elegans. Using C. elegans as a model, we determined that the Salmonella pathogenicity islands-1 and -2 (SPI-1 and SPI-2), PhoP and the virulence plasmid are required for the establishment of a persistent infection. We observed that the PhoP...
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