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Article

OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis.

Journal of lipid research - 1 Feb 2006

Wolins Nathan E, Quaynor Benjamin K, Skinner James R, Tzekov Anatoly, Park Changwon, Choi Kyunghee, Bickel Perry E

Abstract excerpt

Much knowledge of adipocyte biology has been learned from cell culture models, most notably 3T3-L1 cells. The 3T3-L1 model has several limitations, including the requirement of 2 weeks to generate adipocytes and the waning of adipogenic potential in culture. We have investigated the capacity of OP9 cells, a line of bone marrow-derived mouse stromal cells, to recapitulate adipogenesis. When OP9 cells are given any...

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Identifiers

PMID: 16319419
DOI: 10.1194/jlr.D500037-JLR200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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