Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fine mapping of familial prostate cancer families narrows the interval for a susceptibility locus on chromosome 22q12.3 to 1.36 Mb.

Human genetics - 1 Feb 2008

Johanneson Bo, McDonnell Shannon K, Karyadi Danielle M, Hebbring Scott J, Wang Liang, Deutsch Kerry, McIntosh Laura, Kwon Erika M, Suuriniemi Miia, Stanford Janet L, Schaid Daniel J, Ostrander Elaine A, Thibodeau Stephen N

Abstract excerpt

Genetic studies suggest that hereditary prostate cancer is a genetically heterogeneous disease with multiple contributing loci. Studies of high-risk prostate cancer families selected for aggressive disease, analysis of large multigenerational families, and a meta-analysis from the International Consortium for Prostate Cancer Genetics (ICPCG), all highlight chromosome 22q12.3 as a susceptibility locus with strong...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 22
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lod Score

Share to Pedigree

Share to Prostatic Neoplasms

Source

Identifiers

PMID: 18066601
DOI: 10.1007/s00439-007-0451-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fine mapping of familial prostate cancer families narrows the interval for a susceptibility locus on chromosome 22q12.3 to 1.36 Mb.PMID 18066601Read ↗

Compelling evidence for a prostate cancer gene at 22q12.3 by the International Consortium for Prostate Cancer Genetics.Semantic proximity Read ↗

Localization of a prostate cancer predisposition gene to an 880-kb region on chromosome 22q12.3 in Utah high-risk pedigrees.Semantic proximity Read ↗

Family-based association analysis of 42 hereditary prostate cancer families identifies the Apolipoprotein L3 region on chromosome 22q12 as a risk locus.Semantic proximity Read ↗

Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer.Semantic proximity Read ↗

Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families.Semantic proximity Read ↗

A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics.Semantic proximity Read ↗

Genome-wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for Prostate Cancer Genetics using novel sumLINK and sumLOD analyses.Semantic proximity Read ↗

Fine-mapping the putative chromosome 17q21-22 prostate cancer susceptibility gene to a 10 cM region based on linkage analysis.Semantic proximity Read ↗

Comprehensive resequence analysis of a 123-kb region of chromosome 11q13 associated with prostate cancer.Semantic proximity Read ↗

Hereditary prostate cancer in Finland: fine-mapping validates 3p26 as a major predisposition locus.Semantic proximity Read ↗

Genomic search for prostate cancer predisposition loci in Utah pedigrees.Semantic proximity Read ↗

Results of a genome-wide linkage analysis in prostate cancer families ascertained through the ACTANE consortium.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.