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Article

Lipocalin 2‐mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells

6 Dec 2007

Abstract excerpt

Lipocalin 2 (LCN2), a secreted protein of the lipocalin family, induces apoptosis in some types of cells and inhibits bacterial growth by sequestration of the iron-laden bacterial siderophore. We have recently reported that LCN2 inhibits the production of red blood cells in the mouse. Here we analyzed the role of LCN2 in human hematopoiesis. Expression of LCN2 was observed not only in mature cells such as those...

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PMID: 18064607
DOI: 10.1002/jcp.21334

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