Power and validity of methods to identify variability genes.

doi:10.1002/gepi.1370080604

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Article

Power and validity of methods to identify variability genes.

Genetic epidemiology - 1 Jan 1991

Elashoff J D, Cantor R M, Shain S

Abstract excerpt

A variability gene model [Magnus et al., Clin Genet 19:67-70, 1981] hypothesizes that environmental influences on the expression of additive genes for a quantitative trait such as cholesterol are under the control of alleles at a separate nonadditive locus. They suggest identifying such genes usi...

Topics

Aged
Analysis of Variance
Cholesterol
Genetic Variation
Genotype
Humans
Lipoproteins
Male
Triglycerides
Twins, Dizygotic
Twins, Monozygotic

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