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Article

Genetic association in multivariate phenotypic data: power in five models.

Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Dec 2010

Minica Camelia C, Boomsma Dorret I, van der Sluis Sophie, Dolan Conor V

Abstract excerpt

This article concerns the power of various data analytic strategies to detect the effect of a single genetic variant (GV) in multivariate data. We simulated exactly fitting monozygotic and dizygotic phenotypic data according to single and two common factor models, and simplex models. We calculated the power to detect the GV in twin 1 data in an ANOVA of phenotypic sum scores, in a MANOVA, and in exploratory...

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Source

Identifiers

PMID: 21142929
DOI: 10.1375/twin.13.6.525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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